Multidisciplinary Training in Chronic Kidney Disease: from genetic modifiers to drug discovery

According to the 2010 Global Burden of Disease study, CKD was ranked 27th on the list of causes of deaths worldwide in 1990 and rose to 18th in 2010. This drastic jump was second only to that for HIV and AIDs. Currently, the mechanisms of progression of the disease are not well understood including why CKD progresses faster in some people than others. TrainCKDis is supporting 15 young researchers working on projects targeting key areas required to fill the gaps in CKD characterisation. Enhanced understanding will support the identification of biomarkers for early diagnosis of patients most at risk, for monitoring progression, as well as aid in development of treatments.

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About TrainCKDis: 3 objectives

  • Genetics & epigenetics

    Identify genetic variants and epigenetic mechanisms that predispose to CKD progression in the population.

  • Pathways and biomarkers

    Identification of novel pathways and biomarkers able to predict CKD progression rate and treatments benefit.

  • Therapeutic targets

    Uncover novel therapeutic targets and develop innovative therapeutic strategies to slow down CKD progression.